Molecular characterization of the starfish inositol 1,4,5-trisphosphate receptor and its role during oocyte maturation and fertilization.

@article{Iwasaki2002MolecularCO,
  title={Molecular characterization of the starfish inositol 1,4,5-trisphosphate receptor and its role during oocyte maturation and fertilization.},
  author={Hirohide Iwasaki and Kazuyoshi Chiba and Tsuyoshi Uchiyama and Fumio Yoshikawa and Fumiko Suzuki and Masako Ikeda and Teiichi Furuichi and Katsuhiko Mikoshiba},
  journal={The Journal of biological chemistry},
  year={2002},
  volume={277 4},
  pages={2763-72}
}
The release of calcium ions (Ca(2+)) from their intracellular stores is essential for the fertilization of oocytes of various species. The calcium pools can be induced to release Ca(2+) via two main types of calcium channel receptor: the inositol 1,4,5-trisphosphate receptor (IP(3)R) and the ryanodine receptor. Starfish oocytes have often been used to study… CONTINUE READING