Molecular characterization of the androgen receptor gene in boys with hypospadias

@article{Hiort2005MolecularCO,
  title={Molecular characterization of the androgen receptor gene in boys with hypospadias},
  author={O. Hiort and G. Klauber and Mare Cendron and G. H. Sinnecker and L. Keim and E. Schwinger and H. Wolfe and D. Yandell},
  journal={European Journal of Pediatrics},
  year={2005},
  volume={153},
  pages={317-321}
}
  • O. Hiort, G. Klauber, +5 authors D. Yandell
  • Published 2005
  • Biology, Medicine
  • European Journal of Pediatrics
  • Development of male external genitalia is dependent on androgens, and karyotypic males lacking appropriate levels of androgens or functionally normal receptors may show abnormal virilization. Mutations in the androgen receptor gene cause abnormal receptor function and diverser mutations may be associated with heterogenous clinical signs of androgen insensitivity. In this study, we have searched for the existence of androgen receptor gene mutations carried by some patients with hypospadias… CONTINUE READING
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