Molecular characterization of the 5.2 KB isoform of the human cyclooxygenase-1 transcript.

@article{Hla1996MolecularCO,
  title={Molecular characterization of the 5.2 KB isoform of the human cyclooxygenase-1 transcript.},
  author={Timothy Hla},
  journal={Prostaglandins},
  year={1996},
  volume={51 1},
  pages={81-5}
}
Several cDNA clones from human endothelial cells were isolated by expression cloning with the polyclonal antisera against the Ram seminal vesicle cyclooxygenase enzyme (Cox-1). One such clone produced a fusion protein that reacted with two other Cox-1 antiserum (Hla, T., Farrell, M.P., Kumar, A. and Bailey, J.M. (1986) Prostaglandins 32 (6) 829-845). The 2.5 kb cDNA insert was sequenced and contained 60 bp encoding the C-terminal end of the human Cox-1 polypeptide, followed by 2.3 kb of… CONTINUE READING

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