Molecular characterization of prostatic small-cell neuroendocrine carcinoma.

  title={Molecular characterization of prostatic small-cell neuroendocrine carcinoma.},
  author={Nigel Clegg and Camari Ferguson and Lawrence D. True and Hugh Arnold and Alec Moorman and Janna E. Quinn and Robert L. Vessella and Peter S. Nelson},
  journal={The Prostate},
  volume={55 1},
OBJECTIVES A subset of prostate carcinomas is composed predominantly, even exclusively, of neuroendocrine (NE) cells. In this report, we sought to characterize the gene expression profile of a prostate small cell NE carcinoma by assessing the diversity and abundance of transcripts in the LuCaP 49 prostate small cell carcinoma xenograft. METHODS We constructed a cDNA library (PRCA3) from the LuCap 49 prostate small cell xenograft. Single pass DNA sequencing of randomly selected cDNA clones… CONTINUE READING