Molecular characterization of perivascular drainage pathways in the murine brain.

@article{Hannocks2017MolecularCO,
  title={Molecular characterization of perivascular drainage pathways in the murine brain.},
  author={Melanie-Jane Hannocks and Michelle E Pizzo and Jula Huppert and Tushar A Deshpande and N Joan Abbott and Robert G Thorne and Lydia M Sorokin},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  year={2017},
  volume={38 4},
  pages={
          669-686
        }
}
Perivascular compartments surrounding central nervous system (CNS) vessels have been proposed to serve key roles in facilitating cerebrospinal fluid flow into the brain, CNS waste transfer, and immune cell trafficking. Traditionally, these compartments were identified by electron microscopy with limited molecular characterization. Using cellular markers and knowledge on cellular sources of basement membrane laminins, we here describe molecularly distinct compartments surrounding different… CONTINUE READING
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