Molecular characterization of melanocyte stem cells in their niche.

  title={Molecular characterization of melanocyte stem cells in their niche.},
  author={Masatake Osawa and Gyohei Egawa and Siu-Shan Mak and Mariko Moriyama and Rasmus Freter and Saori Yonetani and Friedrich Beermann and Shin-ichi Nishikawa},
  volume={132 24},
Emerging evidence from stem cell (SC) research has strengthened the idea that SC fate is determined by a specialized environment, known as the SC niche. However, because of the difficulty of identifying individual stem cells and their surrounding components in situ, the exact mechanisms underlying SC regulation by the niche remain elusive. To overcome this difficulty, we employed melanocyte stem cells (MSCs), which allow the identification of individual SCs in the niche, the lower permanent… CONTINUE READING
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