Molecular characterization of human zyxin.

  title={Molecular characterization of human zyxin.},
  author={Teresita Macalma and J. -B. Otte and Mary E. Hensler and Susanne M. Bockholt and Heather A. Louis and M. Kalff-Suske and K. H. Grzeschik and Dietmar von der Ahe and Mary C Beckerle},
  journal={The Journal of biological chemistry},
  volume={271 49},
Zyxin is a component of adhesion plaques that has been suggested to perform regulatory functions at these specialized regions of the plasma membrane. Here we describe the isolation and characterization of cDNAs encoding human and mouse zyxin. Both the human and mouse zyxin proteins display a collection of proline-rich sequences as well as three copies of the LIM domain, a zinc finger domain found in many signaling molecules. The human zyxin protein is closely related in sequence to proteins… CONTINUE READING
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