Molecular characterization of hog cholera virus.

  title={Molecular characterization of hog cholera virus.},
  author={Till R{\"u}menapf and Gregor Meyers and Robert H. Stark and H. J. Thiel},
  journal={Archives of virology. Supplementum},
An efficient tissue culture system was established which allowed to obtain substantial quantities of hog cholera virus (HCV) from the cell free tissue culture supernatant. After preparation of viral RNA and cDNA synthesis, the complete HCV genome was cloned and sequenced. Comparison with published BVDV sequences revealed a surprisingly high homology between HCV and BVDV at both the nucleotide and the amino acid level. In addition host cellular sequences were identified in BVDV genomes. The… CONTINUE READING


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