Molecular characterization of feline infectious peritonitis virus strain DF-2 and studies of the role of ORF3abc in viral cell tropism.

@article{Blint2012MolecularCO,
  title={Molecular characterization of feline infectious peritonitis virus strain DF-2 and studies of the role of ORF3abc in viral cell tropism.},
  author={{\'A}d{\'a}m B{\'a}lint and Attila Farsang and Zolt{\'a}n S Z{\'a}dori and {\'A}kos Horny{\'a}k and L{\'a}szl{\'o} Dencső and F. J. Adell Almaz{\'a}n and Luis Enjuanes and S{\'a}nd{\'o}r Bel{\'a}k},
  journal={Journal of virology},
  year={2012},
  volume={86 11},
  pages={6258-67}
}
The full-length genome of the highly lethal feline infectious peritonitis virus (FIPV) strain DF-2 was sequenced and cloned into a bacterial artificial chromosome (BAC) to study the role of ORF3abc in the FIPV-feline enteric coronavirus (FECV) transition. The reverse genetic system allowed the replacement of the truncated ORF3abc of the original FIPV DF-2 genome with the intact ORF3abc of the canine coronavirus (CCoV) reference strain Elmo/02. The in vitro replication kinetics of these two… CONTINUE READING
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A review of feline infectious peritonitis virus infection: 1963–2008

  • NC Pedersen
  • J. Feline Med. Surg
  • 2009
Highly Influential
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