Molecular characterization of envelope antigenic variants of hepatitis B virus from Spain.

@article{Wallace1994MolecularCO,
  title={Molecular characterization of envelope antigenic variants of hepatitis B virus from Spain.},
  author={Lesley A. Wallace and Juan E Echevarr{\'i}a and Jos{\'e} Manuel Echevarr{\'i}a and William F. Carman},
  journal={The Journal of infectious diseases},
  year={1994},
  volume={170 5},
  pages={1300-3}
}
In a survey of hepatitis B virus (HBV) subtypes using one set of monoclonal typing antibodies, 96.6% of the samples were ad or ay and 3.3% (31) were untypeable. Using two additional antibody panels, 23 samples were ay and ad. Six samples required a third panel to be typed as ay. One sample was not typeable. These last 7 samples were nonreactive or had low reactivity with some antibodies to the common a determinant. Sequencing the HBsAg gene of these 7 samples revealed that amino acid (aa) 122… CONTINUE READING

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