Molecular characterization of circulating tumor cells-from bench to bedside.

  title={Molecular characterization of circulating tumor cells-from bench to bedside.},
  author={Yanmeng Li and Shaohan Wu and Fan Bai},
  journal={Seminars in cell & developmental biology},
Circulating tumor cells (CTCs) are cancer cells discovered in cancer patients' peripheral blood that successfully escape from the primary tumor site and/or metastases, struggle to survive in the bloodstream, and have potential for seeding metastases. Numerous methods have been proposed to capture CTCs. The value of CTCs as a means of understanding cancer metastasis and a major form of 'liquid biopsy' has been widely demonstrated. Recently, single-cell molecular analyses of CTCs have provided… CONTINUE READING
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