Molecular characterization of avian influenza H5N1 virus in Egypt and the emergence of a novel endemic subclade.

@article{ElShesheny2014MolecularCO,
  title={Molecular characterization of avian influenza H5N1 virus in Egypt and the emergence of a novel endemic subclade.},
  author={Rabeh El-Shesheny and Ahmed M. Kandeil and Ola Bagato and Asmaa M. Maatouq and Yassmin Moatasim and Adam M. Rubrum and Min-Suk Song and Richard R. J. Webby and Mohamed Ahmed Mohamed Ali and Ghazi Kayali},
  journal={The Journal of general virology},
  year={2014},
  volume={95 Pt 7},
  pages={1444-63}
}
Clade 2.2 highly pathogenic H5N1 viruses have been in continuous circulation in Egyptian poultry since 2006. Their persistence caused significant genetic drift that led to the reclassification of these viruses into subclades 2.2.1 and 2.2.1.1. Here, we conducted full-genome sequence and phylogenetic analyses of 45 H5N1 isolated during 2006-2013 through systematic surveillance in Egypt, and 53 viruses that were sequenced previously and available in the public domain. Results indicated that H5N1… CONTINUE READING
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