Molecular characterization of apocrine carcinoma of the breast: validation of an apocrine protein signature in a well-defined cohort.

@article{Celis2009MolecularCO,
  title={Molecular characterization of apocrine carcinoma of the breast: validation of an apocrine protein signature in a well-defined cohort.},
  author={J. E. Celis and Teresa Cabez{\'o}n and Jos{\'e} M A Moreira and Pavel Gromov and Irina Gromova and Vera Timmermans-Wielenga and Takuji Iwase and Futoshi Akiyama and Naoko Honma and Fritz Rank},
  journal={Molecular oncology},
  year={2009},
  volume={3 3},
  pages={220-37}
}
Invasive apocrine carcinomas (IACs), as defined by morphological features, correspond to 0.3-4% of all invasive ductal carcinomas (IDC), and despite the fact that they are histologically distinct from other breast lesions there are currently no standard molecular criteria available for their diagnosis and no unequivocal information as to their prognosis. In an effort to address these concerns we have been using protein expression profiling technologies in combination with mass spectrometry and… CONTINUE READING

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