Molecular characterization of an autolysin-defective mutant of Streptococcus pneumoniae.

Abstract

The mutant gene lyt-4 of the autolysin-defective mutant R6ly4-4 of Streptococcus pneumoniae, which synthesized a temperature-sensitive autolytic enzyme, has been cloned in Escherichia coli. The nucleotide defect of the lyt-4 mutation has been characterized as a CG to TA transition. This transition causes the appearance of a glutamic acid instead of a… (More)

Topics

Cite this paper

@article{Garcia1986MolecularCO, title={Molecular characterization of an autolysin-defective mutant of Streptococcus pneumoniae.}, author={Juan Luis Garcia and Jos{\'e} Mar{\'i}a S{\'a}nchez-Puelles and Pilar Peral Garc{\'i}a and Rubens L{\'o}pez and Concepci{\'o}n Ronda and Eulogio J. Garc{\'i}a}, journal={Biochemical and biophysical research communications}, year={1986}, volume={137 2}, pages={614-9} }