Molecular characterization of alpha-Thalassemia in Adana, Turkey: A single center study.

@article{Guvenc2010MolecularCO,
  title={Molecular characterization of alpha-Thalassemia in Adana, Turkey: A single center study.},
  author={Birol Guvenc and Sule Menziletoglu Yildiz and Ferda Tekinturhan and Suleyman Dincer and Inci Akyuzluer and Secaatin Okten and Hakan Erkman},
  journal={Acta haematologica},
  year={2010},
  volume={123 4},
  pages={197-200}
}
BACKGROUND/AIM alpha-Thalassemia (alpha-thal) is a widespread genetic disorder throughout the world caused primarily by reduced synthesis of the alpha-globin chains, and it has been found at a high incidence in Turkey. Our aim in this study was to determine the frequency and molecular properties of alpha-thal in Adana, Turkey. MATERIAL AND METHODS A total of 3,000 individuals comprising premarital couples or patients with anemia were screened between 2007 and 2008. Hematological parameters… CONTINUE READING