Molecular characterization of a peripheral receptor for cannabinoids

@article{Munro1993MolecularCO,
  title={Molecular characterization of a peripheral receptor for cannabinoids},
  author={S. Munro and K. Thomas and M. Abu-Shaar},
  journal={Nature},
  year={1993},
  volume={365},
  pages={61-65}
}
THE major active ingredient of marijuana, Δ9-tetrahydrocannabi-nol (Δ9-THC), has been used as a psychoactive agent for thousands of years. Marijuana, and Δ9-THC, also exert a wide range of other effects including analgesia, anti-inflammation, immunosuppression, anticonvulsion, alleviation of intraocular pressure in glaucoma, and attenuation of vomiting1. The clinical application of cannabinoids has, however, been limited by their psychoactive effects, and this has led to interest in the… Expand
The endocannabinoid nervous system: unique opportunities for therapeutic intervention.
A molecular basis of the therapeutic and psychoactive properties of cannabis (Δ9-tetrahydrocannabinol)
The effects of cannabinoids on the brain
  • A. Ameri
  • Medicine, Chemistry
  • Progress in Neurobiology
  • 1999
Molecular neurobiology of the cannabinoid receptor.
From cannabis to cannabinergics: new therapeutic opportunities.
Therapeutic potential of cannabinoid-based drugs.
Endocannabinoids in the retina: From marijuana to neuroprotection
  • S. Yazulla
  • Medicine, Biology
  • Progress in Retinal and Eye Research
  • 2008
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 28 REFERENCES
A novel probe for the cannabinoid receptor.
Cannabinoid receptor localization in brain.
  • M. Herkenham, A. Lynn, +4 authors K. Rice
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 1990
Pharmacological activity of the cannabinoid receptor agonist, anandamide, a brain constituent.
...
1
2
3
...