Molecular characterization of a novel immune receptor restricted to the monocytic lineage.

@article{Aguilar2004MolecularCO,
  title={Molecular characterization of a novel immune receptor restricted to the monocytic lineage.},
  author={Helena Aguilar and Damiana {\'A}lvarez-Errico and Andr{\'e}s C. Garc{\'i}a-Montero and Alberto Orfao and Joan Say{\'o}s and Miguel L{\'o}pez-Botet},
  journal={Journal of immunology},
  year={2004},
  volume={173 11},
  pages={6703-11}
}
Homology basic local alignment search tool search was conducted using a sequence encoding for a novel inhibitory receptor (IREM-1) cloned in our laboratory and a previously described homologous sequence termed CMRF-35. On the basis of this information, we cloned a full length cDNA corresponding to a novel member of this family, termed immune receptor expressed by myeloid cells 2 (IREM-2). The gene, located in chromosome 17q25.1, encodes for a protein of 205 aa that contains an extracellular… CONTINUE READING