Molecular characterization of a heteromeric ATP-citrate lyase that generates cytosolic acetyl-coenzyme A in Arabidopsis.

@article{Fatland2002MolecularCO,
  title={Molecular characterization of a heteromeric ATP-citrate lyase that generates cytosolic acetyl-coenzyme A in Arabidopsis.},
  author={Beth L Fatland and Jinshan Ke and Marc D. Anderson and Wieslawa I. Mentzen and Li Cui and Carolyn C. Allred and Jerry L Johnston and Basil J. Nikolau and Eve Syrkin Wurtele},
  journal={Plant physiology},
  year={2002},
  volume={130 2},
  pages={740-56}
}
Acetyl-coenzyme A (CoA) is used in the cytosol of plant cells for the synthesis of a diverse set of phytochemicals including waxes, isoprenoids, stilbenes, and flavonoids. The source of cytosolic acetyl-CoA is unclear. We identified two Arabidopsis cDNAs that encode proteins similar to the amino and carboxy portions of human ATP-citrate lyase (ACL). Coexpression of these cDNAs in yeast (Saccharomyces cerevisiae) confers ACL activity, indicating that both the Arabidopsis genes are required for… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 85 references

Regulation of the pyruvate dehydrogenase complexes in plants

D Rangasamy, C Ratledge
Ann NY Acad Sci • 2000
View 5 Excerpts
Highly Influenced

Molecular biology of acetyl - CoA generation

ES Wurtele, RH Behal, +6 authors PS Schnable
Advances in Plant Lipid Research • 1998
View 4 Excerpts
Highly Influenced

Purification and characterization of acetyl coenzyme A : 10 - hydroxytaxane O - acetyltransferase from cell suspension cultures of Taxus chinensis

K Nakai, M Kanehisa
Phytochemistry • 1992
View 4 Excerpts
Highly Influenced

PHYLIP : Phylogeny Inference Package , version 32

J Felsenstein
Cladistics • 1989
View 1 Excerpt
Highly Influenced

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