Molecular characterization of a phospholipid-hydroperoxide glutathione peroxidase from the bumblebee Bombus ignitus.

@article{Hu2010MolecularCO,
  title={Molecular characterization of a phospholipid-hydroperoxide glutathione peroxidase from the bumblebee Bombus ignitus.},
  author={Zhigang Hu and Kwang Sik Lee and Young Moo Choo and Hyung Joo Yoon and Iksoo Kim and Ya Dong Wei and Zhongzheng Gui and Guo Zheng Zhang and Hung Dae Sohn and Byung Rae Jin},
  journal={Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology},
  year={2010},
  volume={155 1},
  pages={54-61}
}
Phospholipid-hydroperoxide glutathione peroxidase (PHGPx or GPx4; EC 1.11.1.12) is an antioxidant enzyme that reduces lipid hydroperoxides in biomembranes. Here, we cloned and characterized cys-PHGPx from the bumblebee Bombus ignitus (Bi-PHGPx). The Bi-PHGPx gene consists of 4 exons, encoding 168 amino acid residues with a canonical cys-codon at residue 45… CONTINUE READING