Molecular characterization of a genomic region associated with virulence in Dichelobacter nodosus.

@article{Katz1992MolecularCO,
  title={Molecular characterization of a genomic region associated with virulence in Dichelobacter nodosus.},
  author={Margaret E. Katz and Richard A. Strugnell and Julian I Rood},
  journal={Infection and immunity},
  year={1992},
  volume={60 11},
  pages={4586-92}
}
The major pathogen implicated in footrot, a highly contagious disease of sheep, is the strict anaerobe Dichelobacter nodosus (formerly Bacteroides nodosus). Sequence analysis of a 2,262-bp segment of the D. nodosus genome which is more prevalent in virulent isolates than in other isolates showed the presence of four open reading frames which appeared to have consensus transcriptional and translational start signals. These virulence-associated genes have been designated vapABCD. Two of the three… CONTINUE READING

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