Molecular characterization of Vibrio cholerae O1 strains isolated in Romania.

  title={Molecular characterization of Vibrio cholerae O1 strains isolated in Romania.},
  author={Mirela Damian and S Koblavi and Isabelle Carle and Nadia Năcescu and Francine Grimont and C Ciufecu and Patrick A D Grimont},
  journal={Research in microbiology},
  volume={149 10},
A collection of 89 Vibrio cholerae O1 strains, isolated in Romania between 1977 and 1994, and 6 strains from the Republic of Moldavia, was characterized by ribotyping, toxin gene restriction pattern (toxinogenotype) and distribution of cholera toxin gene (ctx), accessory toxin gene (ace) and zonula occludens toxin gene (zot). After Bg/I endonuclease restriction of chromosomal DNA, a total of 18 ribotypes and 21 toxinogenotypes were distinguished. Deletions in the core region of the toxin gene… CONTINUE READING

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