Molecular characterization of Ph1 as a major chromosome pairing locus in polyploid wheat

@article{Griffiths2006MolecularCO,
  title={Molecular characterization of Ph1 as a major chromosome pairing locus in polyploid wheat},
  author={Simon Griffiths and R Sharp and Tracie N. Foote and Isabelle Bertin and Michael K. Wanous and Stephen M. Reader and Isabelle Colas and Graham Moore},
  journal={Nature},
  year={2006},
  volume={439},
  pages={749-752}
}
The foundation of western civilization owes much to the high fertility of bread wheat, which results from the stability of its polyploid genome. Despite possessing multiple sets of related chromosomes, hexaploid (bread) and tetraploid (pasta) wheat both behave as diploids at meiosis. Correct pairing of homologous chromosomes is controlled by the Ph1 locus. In wheat hybrids, Ph1 prevents pairing between related chromosomes. Lack of Ph1 activity in diploid relatives of wheat suggests that Ph1… 
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TLDR
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TLDR
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TLDR
The relationship between the Ph1 cyclin-dependent kinase (CDK)-like genes in wheat and the CDK2 genes in mammals and their involvement in controlling this process at meiosis is examined.
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