Molecular characterization of L-amino acid oxidase from Agkistrodon halys blomhoffii with special reference to platelet aggregation.

@article{Takatsuka2001MolecularCO,
  title={Molecular characterization of L-amino acid oxidase from Agkistrodon halys blomhoffii with special reference to platelet aggregation.},
  author={Hideo Takatsuka and Yoshihiko Sakurai and A. Yoshioka and Tetsuro Kokubo and Yoshiko Usami and M. Suzuki and Taei Matsui and Koiti Titani and Hideo Yagi and Masanori Matsumoto and Yoshihiro Fujimura},
  journal={Biochimica et biophysica acta},
  year={2001},
  volume={1544 1-2},
  pages={
          267-77
        }
}
L-Amino acid oxidase (LAO, EC 1.4.3.2) is widely distributed in snake venom, and induces apoptosis in vascular endothelial cells, causing prolonged bleeding from vessel walls at bite sites. The effect of snake venom LAOs on platelet function is controversial. Further, we have little information on their structural characterization. We purified M (mamushi)-LAO, a single-chain glycoprotein with a molecular mass of 60 kDa and a pI of 4.9, from Agkistrodon halys blomhoffii (Japanese mamushi) venom… Expand
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TLDR
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Purification and characterization of a new L-amino acid oxidase from Daboia russellii siamensis venom.
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  • Biology, Medicine
  • Toxicon : official journal of the International Society on Toxinology
  • 2009
TLDR
Results showed that DRS-LAAO had the strongest antimicrobial activity against S. aureus among these three international standard stains. Expand
Cloning, characterization and mutagenesis of Russell's viper venom L-amino acid oxidase: Insights into its catalytic mechanism.
TLDR
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