Molecular characterization and functional properties of cardiomyocytes derived from human inducible pluripotent stem cells

@article{Germanguz2011MolecularCA,
  title={Molecular characterization and functional properties of cardiomyocytes derived from human inducible pluripotent stem cells},
  author={I. Germanguz and Oshra Sedan and N. Zeevi-Levin and R. Shtrichman and E. Barak and A. Ziskind and S. Eliyahu and G. Meiry and M. Amit and J. Itskovitz-Eldor and O. Binah},
  journal={Journal of Cellular and Molecular Medicine},
  year={2011},
  volume={15},
  pages={38 - 51}
}
  • I. Germanguz, Oshra Sedan, +8 authors O. Binah
  • Published 2011
  • Medicine, Biology
  • Journal of Cellular and Molecular Medicine
  • Abstract In view of the therapeutic potential of cardiomyocytes derived from induced pluripotent stem (iPS) cells (iPS-derived cardiomyocytes), in the present study we investigated in iPS-derived cardiomyocytes, the functional properties related to [Ca2+]i handling and contraction, the contribution of the sarcoplasmic reticulum (SR) Ca2+ release to contraction and the b-adrenergic inotropic responsiveness. The two iPS clones investigated here were generated through infection of human foreskin… CONTINUE READING
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