Molecular characterization and functional expression of a substance P receptor from the sympathetic ganglion of Rana catesbeiana.

@article{Simmons1997MolecularCA,
  title={Molecular characterization and functional expression of a substance P receptor from the sympathetic ganglion of Rana catesbeiana.},
  author={M Abigail Simmons and Robbin M Brodbeck and Vladimir V Karpitskiy and C. R. Schneider and David P. A. Neff and James E. Krause},
  journal={Neuroscience},
  year={1997},
  volume={79 4},
  pages={1219-29}
}
Substance P is an important neuropeptide neurotransmitter in the central, autonomic and enteric nervous systems. In sympathetic ganglia, substance P is thought to play a role in modulating synaptic transmission. Release of substance P by neuronal stimulation or direct application of substance P to ganglionic neurons increases neuronal excitability. An amphibian substance P receptor complementary DNA has been cloned and characterized from bullfrog, Rana catesbeiana, sympathetic ganglion… CONTINUE READING

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