Molecular characterization and expression of urotensin II and its receptor in the flounder (Platichthys flesus): a hormone system supporting body fluid homeostasis in euryhaline fish.

@article{Lu2006MolecularCA,
  title={Molecular characterization and expression of urotensin II and its receptor in the flounder (Platichthys flesus): a hormone system supporting body fluid homeostasis in euryhaline fish.},
  author={Weiqun Lu and Michael M. Greenwood and Louise Dow and Janette Yuill and Jonathan Worthington and Matthew J Brierley and Catherine R. McCrohan and Daniela Riccardi and Richard John Balment},
  journal={Endocrinology},
  year={2006},
  volume={147 8},
  pages={3692-708}
}
Urotensin II (UII) is a potent vasoconstrictor in mammals, but the source of circulating UII remains unclear. Investigations of the caudal neurosecretory system (CNSS), considered the major source of UII in fish, alongside target tissue expression of UII receptor (UT), can provide valuable insights into this highly conserved regulatory system. We report UII gene characterization, expression of the first fish UT, and responses to salinity challenge in flounder. The 12-aa UII peptide shares 73… CONTINUE READING