Molecular characterization and expression analysis of complement component 3 in dojo loach (Misgurnus anguillicaudatus).

@article{Xu2018MolecularCA,
  title={Molecular characterization and expression analysis of complement component 3 in dojo loach (Misgurnus anguillicaudatus).},
  author={Yongsheng Xu and Yongyao Yu and Xiaoting Zhang and Zhenyu Huang and Huili Li and Shuai Dong and Yangzhou Liu and Fen Dong and Zhen Xu},
  journal={Fish & shellfish immunology},
  year={2018},
  volume={72},
  pages={
          484-493
        }
}
The complement component 3 (C3) is a central component of complement system. All three pathways converge at formation of C3 convertases and share the terminal pathways of membrane attack complex (MAC) formation. In this study, three isoforms of C3 were discovered in Misgurnus anguillicaudatus, named "C3-1", "C3-2" and "C3-3", respectively. The full-length of C3-1 cDNA sequence was firstly identified and analyzed from dojo loach (Misgurnus anguillicaudatus). The Ma-C3-1 cDNA sequence comprised… CONTINUE READING