Molecular characterization and cell-specific expression of an ion transport peptide in the tobacco hornworm, Manduca sexta

  title={Molecular characterization and cell-specific expression of an ion transport peptide in the tobacco hornworm, Manduca sexta},
  author={Anna L. Drexler and Christina C. Harris and Myra G. Pena and Marilyn Asuncion-Uchi and Sook Chung and Simon George Webster and Megumi Fuse},
  journal={Cell and Tissue Research},
The crustacean hyperglycemic hormone (CHH) peptides regulate diverse physiological processes from reproduction to metabolism and molting in arthropods. In insects, the ion transport peptides (ITP), also members of the CHH family, have only been implicated in ion transport. In this study, we sequenced a nucleotide fragment spanning the conserved A1/A2 region of the putative CHH/ITP gene. This fragment was amplified from larval cDNA of the tobacco hornworm, Manduca sexta and showed a high degree… 
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Developmental and regional-specific expression of FLRFamide peptides in the tobacco hornworm, Manduca sexta, suggests functions at ecdysis.
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Occurrence of ion transport peptide (ITP) and ion transport-like peptide (ITP-L) in orthopteroids.
Results indicate high conservation of ITP structure and biological activity among these orthopteroids, in contrast to several other insect orders.
Isolation and expression of the eclosion hormone gene from the tobacco hornworm, Manduca sexta.
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