Molecular characterization and cell-specific expression of an ion transport peptide in the tobacco hornworm, Manduca sexta

@article{Drexler2007MolecularCA,
  title={Molecular characterization and cell-specific expression of an ion transport peptide in the tobacco hornworm, Manduca sexta},
  author={Anna L. Drexler and Christina C. Harris and Myra G. Pena and Marilyn Asuncion-Uchi and Sook Chung and Simon George Webster and Megumi Fuse},
  journal={Cell and Tissue Research},
  year={2007},
  volume={329},
  pages={391-408}
}
The crustacean hyperglycemic hormone (CHH) peptides regulate diverse physiological processes from reproduction to metabolism and molting in arthropods. In insects, the ion transport peptides (ITP), also members of the CHH family, have only been implicated in ion transport. In this study, we sequenced a nucleotide fragment spanning the conserved A1/A2 region of the putative CHH/ITP gene. This fragment was amplified from larval cDNA of the tobacco hornworm, Manduca sexta and showed a high degree… 
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Functions of ion transport peptide and ion transport peptide-like in the red flour beetle Tribolium castaneum.
The CHH-superfamily of multifunctional peptide hormones controlling crustacean metabolism, osmoregulation, moulting, and reproduction.
Molecular cloning of the crustacean hyperglycemic hormone (CHH) precursor from the X-organ and the identification of the neuropeptide from sinus gland of the Alaskan Tanner crab, Chionoecetes bairdi.
Molecular Disruption of Ion Transport Peptide Receptor Results in Impaired Water Homeostasis and Developmental Defects in Bombyx mori
TLDR
The data show that ITPR plays key roles in regulating insect water homeostasis and development and key genes in insulin and ecdysone signaling pathways were also affected by BNGR-A2 disruption.
Identification and Characterization of Receptors for Ion Transport Peptide (ITP) and ITP-like (ITPL) in the Silkworm Bombyx mori*
TLDR
Three Bombyx mori orphan neuropeptide G protein-coupled receptors are identified as receptors for ITP and ITPL (collectively referred to as ITPs), demonstrating that BngR-A2 and -A34 are ITP receptors and that BNGR- a24 is an ITPL receptor in B. mori.
Insect ion transport peptides are derived from alternatively spliced genes and differentially expressed in the central and peripheral nervous system
TLDR
The comparative data on the highly similar gene, precursor and primary structures and similar differential distributions in insect and crustacean NSCs suggest that CHH/ITP and ITPL neuropeptide-producing cells and their gene products share common phylogenetic ancestry.
Crustacean hyperglycemic hormone (CHH) neuropeptidesfamily: Functions, titer, and binding to target tissues.
The Crustacean Hyperglycemic Hormone Superfamily: Progress Made in the Past Decade
TLDR
The widespread identification of the CHH-superfamily peptides, in particular in non-crustaceans, which has reshaped the phylogenetic profile of the superfamily and the first-ever identification ofThe receptors for ITPs of the silkworm, which will surely give great impetus to the functional study of these peptides for years to come.
Leucokinins: Multifunctional Neuropeptides and Hormones in Insects and Other Invertebrates
TLDR
Functional roles of LK signaling include regulation of ion and water homeostasis, feeding, sleep–metabolism interactions, state-dependent memory formation, as well as modulation of gustatory sensitivity and nociception.
Seminal fluid protein genes of the brown planthopper, Nilaparvata lugens
TLDR
This work represents the first characterization of putative SFPs in a hemipeteran species and provides a foundation for future studies to investigate the functions of SFPS in N. lugens.
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