Molecular characteristics of Na(+)-coupled glucose transporters in adult and embryonic rat kidney.

@article{You1995MolecularCO,
  title={Molecular characteristics of Na(+)-coupled glucose transporters in adult and embryonic rat kidney.},
  author={Guofeng You and W S Lee and Elivo J. G. Barros and Yoshikatsu Kanai and T L Huo and Saira Khawaja and Robert G Wells and Sanjay K. Nigam and Matthias A. Hediger},
  journal={The Journal of biological chemistry},
  year={1995},
  volume={270 49},
  pages={29365-71}
}
Two distinct Na(+)-coupled glucose transporters (SGLTs) with either a high or a low affinity for glucose were shown to provide reabsorption of filtered glucose in the kidney. We have previously reported the characteristics of the high affinity Na+/glucose cotransporter SGLT1 from rabbit, rat, and human kidney and the low affinity Na+/glucose cotransporter SGLT2 from human kidney. Because the molecular identity of SGLT2 as the kidney cortical low affinity Na+/glucose cotransporter has been… CONTINUE READING
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