Molecular characteristics of IgA in infant saliva.

  title={Molecular characteristics of IgA in infant saliva.},
  author={Allan Cripps and Maree Gleeson and Robert L. Clancy},
  journal={Scandinavian journal of immunology},
  volume={29 3},
Saliva was collected from 57 infants aged 6 weeks to 2.5 years and the molecular form of IgA was studied by centrifugation on sucrose density gradients. Two distinct populations were identified. Seventy-two per cent of the children had secretory IgA in their salivary secretions, while 28% had a molecular form corresponding to monomeric IgA. No samples with concurrent monomeric and secretory forms were detected. Monomeric IgA was not detected in any infant over 12 months of age. Secretory… CONTINUE READING