Molecular characterisation of the 3′-end of the astrovirus genome

@article{Monceyron1997MolecularCO,
  title={Molecular characterisation of the 3′-end of the astrovirus genome},
  author={C. Monceyron and Bj{\o}rn Grinde and Tom {\O}ystein Jonassen},
  journal={Archives of Virology},
  year={1997},
  volume={142},
  pages={699-706}
}
We have sequenced the 3′-end of the RNA genomes of 14 serotyped and 12 untyped isolates of human astrovirus. The sequences, which include all 8 serotypes, were used to predict secondary structures, postulate possible functional domains, reveal conserved regions suitable for nucleic acid amplification and perform phylogenetic analysis. The final nucleotides of the capsid protein precursor gene and the adjacent 3′-noncoding region were highly conserved and, except for 35 nucleotides with homology… CONTINUE READING
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