Molecular characterisation of antidepressant effects in the mouse brain using gene expression profiling.

@article{Landgrebe2002MolecularCO,
  title={Molecular characterisation of antidepressant effects in the mouse brain using gene expression profiling.},
  author={Jobst Landgrebe and Gerhard Welzl and Thomas Metz and Marcel M. van Gaalen and H Hilger Ropers and Wolfgang Wurst and Florian Holsboer},
  journal={Journal of psychiatric research},
  year={2002},
  volume={36 3},
  pages={119-29}
}
Antidepressants are widely used for the treatment of psychiatric disorders, including depression and anxiety. Although they are efficient drugs, there are several unsolved questions regarding their clinical pharmacology. Furthermore, the molecular mechanisms of action of antidepressants are still poorly understood and the molecular targets and pathways remain to be identified. To address these issues, we performed a gene expression analysis in mice treated with two commonly used antidepressants… CONTINUE READING

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