Molecular characterisation and inductive expression of a fish protein arginine methyltransferase 1 gene in response to virus infection.

@article{Dong2007MolecularCA,
  title={Molecular characterisation and inductive expression of a fish protein arginine methyltransferase 1 gene in response to virus infection.},
  author={Cai-Wen Dong and Yibing Zhang and Ai-jun Lu and Rong Zhu and Fu-Tie Zhang and Qi-ya Zhang and Jian-Fang Gui},
  journal={Fish & shellfish immunology},
  year={2007},
  volume={22 4},
  pages={380-93}
}
Protein arginine methyltransferase 1 (PRMT1) is currently thought as an effector to regulate interferon (IFN) signalling. Here Paralichthys olivaceus PRMT1 (PoPRMT1) gene was identified as a virally induced gene from UV-inactivated Scophthalmus maximus Rhabdovirus (SMRV)-infected flounder embryonic cells (FEC). PoPMRT1 encodes a 341-amino-acid protein that shares the conserved domains including post-I, motif I, II and III. Homology comparisons show that the putative PoPMRT1 protein is the… CONTINUE READING