Molecular chaperones in Parkinson's disease--present and future.

@article{EbrahimiFakhari2011MolecularCI,
  title={Molecular chaperones in Parkinson's disease--present and future.},
  author={Darius Ebrahimi-Fakhari and Lara Wahlster and Pamela J McLean},
  journal={Journal of Parkinson's disease},
  year={2011},
  volume={1 4},
  pages={
          299-320
        }
}
Parkinson's disease, like many other neurodegenerative disorders, is characterized by the progressive accumulation of pathogenic protein species and the formation of intracellular inclusion bodies. The cascade by which the small synaptic protein α-synuclein misfolds to form distinctive protein aggregates, termed Lewy bodies and Lewy neurites, has been the subject of intensive research for more than a decade. Genetic and pathological studies in Parkinson's disease patients as well as… CONTINUE READING

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