Molecular changes associated with the transmission of avian influenza a H5N1 and H9N2 viruses to humans.

@article{Shaw2002MolecularCA,
  title={Molecular changes associated with the transmission of avian influenza a H5N1 and H9N2 viruses to humans.},
  author={Michael W. Shaw and Laurence J. N. Cooper and Xiwei Xu and William Thompson and Scott Krauss and Yi Guan and Nannan Zhou and Alexander Klimov and Nancy A Cox and Robert James Webster and Wilina Wei Ling Lim and K Shortridge and Kanta Subbarao},
  journal={Journal of medical virology},
  year={2002},
  volume={66 1},
  pages={107-14}
}
In order to identify molecular changes associated with the transmission of avian influenza A H5N1 and H9N2 viruses to humans, the internal genes from these viruses were compared to sequences from other avian and human influenza A isolates. Phylogenetically, each of the internal genes of all sixteen of the human H5N1 and both of the H9N2 isolates were closely related to one another and fell into a distinct clade separate from clades formed by the same genes of other avian and human viruses. All… CONTINUE READING

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