Molecular biology of unreresectable meningiomas: implications for new treatments and review of the literature.

@article{Jagannathan2008MolecularBO,
  title={Molecular biology of unreresectable meningiomas: implications for new treatments and review of the literature.},
  author={J. Jagannathan and Rod J. Oskouian and Hian Kwang Yeoh and Dwight Saulle and Aaron Sean Dumont},
  journal={Skull base : official journal of North American Skull Base Society ... [et al.]},
  year={2008},
  volume={18 3},
  pages={173-87}
}
Even though meningiomas are most often benign tumors, they can be locally invasive and can develop in locations that prevent surgical treatment. The molecular and biologic factors underlying meningioma development are only now beginning to be understood. Genetic factors such as mutations in the neurofibromatosis-2 gene and in chromosomes 1, 9, and 10 play… CONTINUE READING