Molecular biology of the insulin-like growth factors

  title={Molecular biology of the insulin-like growth factors},
  author={Jessie English Hepler and Pauline Kay Lund},
  journal={Molecular Neurobiology},
In the past ten years, molecular biology approaches have provided the structures of multiple components of the IGF system, IGF peptides, receptors, binding proteins, and the mRNAs and genes encoding them. Progress has been made toward understanding which components of the IGF system are expressed in the nervous system, their cellular localization, and their regulation. The molecular studies also provide the potential for availability of pure components of the IGF system for testing of… CONTINUE READING
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