Molecular biology of rotaviruses. V. Terminal structure of viral RNA species.


The terminal structure of rotavirus genomic ds RNA and in vitro transcribed mRNA was investigated using S1 nuclease digestion and 3' terminal sequence analysis. S1 nuclease analysis indicated that viral mRNA was not a truncated copy of the genome RNA at its 5' end. The 3' terminal sequence analysis of genomic plus strands and mRNA showed that they were… (More)


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