Molecular biology of nervous system tumors.

  • Shirley Rempel
  • Published 2001 in Hematology/oncology clinics of North America


Many genetic alterations that contribute to CNS tumorigenesis and progression have been identified. One goal of such studies is to identify loci that would serve as diagnostic prognostic markers or both. A significant advance is the observation that chromosome 1p loss identified anaplastic oligodendroglioma and a subset of high-grade glioma patients who… (More)


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