Molecular biology of metabolic disease: defects in the regulation of enzymic activity.

Abstract

The Jacob-Monod model for the regulation of enzymic activity has been used in the analysis of some types of metabolic disease. Three lesions have been considered: (1) loss of allosteric inhibition of phosphofructokinase by citrate in the condition of lipomatosis; (2) failure of covalent modification of triglyceride lipase from inactive to active forms in… (More)

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Cite this paper

@article{Galton1978MolecularBO, title={Molecular biology of metabolic disease: defects in the regulation of enzymic activity.}, author={D. J. Galton}, journal={Enzyme}, year={1978}, volume={23 4}, pages={274-88} }