Molecular biology of angiotensin receptors and their role in human cardiovascular disease

@article{RegitzZagrosek1996MolecularBO,
  title={Molecular biology of angiotensin receptors and their role in human cardiovascular disease},
  author={V. Regitz-Zagrosek and M. Neu{\ss} and J. Holzmeister and C. Warnecke and E. Fleck},
  journal={Journal of Molecular Medicine},
  year={1996},
  volume={74},
  pages={233-251}
}
  • V. Regitz-Zagrosek, M. Neuß, +2 authors E. Fleck
  • Published in Journal of Molecular Medicine 1996
  • DOI:10.1007/BF00196577
The actions of angiotensin II in the cardiovascular system are transmitted by two known and possibly some unknown angiotensin receptor types. AT1 and AT2 both correspond to G-protein-coupled receptors with seven hydrophobic transmembrane domains, several N-glycosylation sites and a potential G-protein binding site. Cloning of coding regions and promoter sequences contributed to the understanding of receptor protein function and regulation. Angiotensin receptors with atypical binding properties… CONTINUE READING

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