Molecular biology of angiotensin receptors: target for drug research?

  title={Molecular biology of angiotensin receptors: target for drug research?},
  author={Victor J. Dzau and Masashi Mukoyama and Richard E. Pratt},
  journal={Journal of hypertension. Supplement : official journal of the International Society of Hypertension},
  volume={12 2},
UNLABELLED Angiotensin II receptors: Angiotensin II is a key regulator of cardiovascular homeostasis. At least two distinct angiotensin II receptor subtypes are defined, on the basis of their differential pharmacological and biochemical properties, and designated as type 1 (AT1) and type 2 (AT2) receptors. AT1 subtypes: Recent cloning has revealed that the AT1 type belongs to a seven-transmembrane, G protein-coupled receptor superfamily. The AT1 receptor comprises two isoforms, AT1a and AT1b… CONTINUE READING


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