Molecular biology of 5-HT receptors

@article{Boess1994MolecularBO,
  title={Molecular biology of 5-HT receptors},
  author={F. Boess and I. Martin},
  journal={Neuropharmacology},
  year={1994},
  volume={33},
  pages={275-317}
}
The receptors through which serotonin (5-hydroxytryptamine, 5-HT) produces its effects have been the subject of intense investigation, initially using both in vivo and in vitro pharmacological methods, and later radioligand binding. These approaches allowed a preliminary classification of 5-HT receptors, but the identification on subtypes was limited by the selectivity on the available agonists and antagonists. Bradley et al. (1986) distinguished three main classes of 5-HT receptors: 5-HT 1 , 5… Expand
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