Molecular biology and ontogeny of gamma-aminobutyric acid (GABA) receptors in the mammalian central nervous system.

Abstract

gamma-Aminobutyric acid (GABA) is the predominant inhibitory neurotransmitter in the mammalian central nervous system. After release from nerve terminals, GABA binds to at least two classes of postsynaptic receptors (ie, GABAA and GABAB), which are nearly ubiquitous in the brain. GABAA receptors are postsynaptic heteropentameric complexes that display… (More)

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@article{Simeone2003MolecularBA, title={Molecular biology and ontogeny of gamma-aminobutyric acid (GABA) receptors in the mammalian central nervous system.}, author={Timothy A. Simeone and Sean D Donevan and Jong M. Rho}, journal={Journal of child neurology}, year={2003}, volume={18 1}, pages={39-48; discussion 49} }