Molecular basisof agonism andantagonism in the oestrogen receptor

@inproceedings{BrzozowskiMolecularBA,
  title={Molecular basisof agonism andantagonism in the oestrogen receptor},
  author={Andrzej M Brzozowski and Ashley C W Pike and Zbigniew Dauter and Roderick E. Hubbard and Tomas Bonn and Owe Engstr{\"o}m and Lars – Daniel {\"O}hman and Geoffrey L Greene and Jan-{\AA}ke Gustafsson and Mats Carlquist}
}
753 recent observation that activation of P2X receptors on neurites of identified nociceptors induces firing of action potentials 20. In that study 20 it was suggested that P2X receptors localized at peripheral sensory nerve terminals provide a mechanism for sensing noci-ceptive stimulation. Thus it is possible that P2X receptors expressed on both the peripheral terminals and central presynaptic terminals are capable of modulating or generating nociceptive signalling. Ⅺ Methods Cell cultures… CONTINUE READING

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