Molecular basisof agonism andantagonism in the oestrogen receptor

  title={Molecular basisof agonism andantagonism in the oestrogen receptor},
  author={Andrzej M Brzozowski and Ashley C W Pike and Zbigniew Dauter and Roderick E. Hubbard and Tomas Bonn and Owe Engstr{\"o}m and Lars – Daniel {\"O}hman and Geoffrey L Greene and Jan-{\AA}ke Gustafsson and Mats Carlquist}
753 recent observation that activation of P2X receptors on neurites of identified nociceptors induces firing of action potentials 20. In that study 20 it was suggested that P2X receptors localized at peripheral sensory nerve terminals provide a mechanism for sensing noci-ceptive stimulation. Thus it is possible that P2X receptors expressed on both the peripheral terminals and central presynaptic terminals are capable of modulating or generating nociceptive signalling. Ⅺ Methods Cell cultures… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
10 Extracted Citations
44 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 10 extracted citations

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 44 references

Structure - activity relationships of selective estrogen receptor modulators : Modifications to the 2 - arylbenzothiophene core of raloxifene

  • T. A. Grese
  • J . Med . Chem .
  • 1997

A controlled trial of raloxifene ( LY 139481 ) HCl : Impact on bone turnover and serum lipid profile in healthy postmenopausal women

  • M. W. Draper
  • J . Bone Miner . Res .
  • 1996

Similar Papers

Loading similar papers…