Molecular basis of transcriptional fidelity and DNA lesion-induced transcriptional mutagenesis.

@article{Xu2014MolecularBO,
  title={Molecular basis of transcriptional fidelity and DNA lesion-induced transcriptional mutagenesis.},
  author={Liang Xu and Linati Da and Steven W. Plouffe and Jenny Chong and Eric T. Kool and Dong Wang},
  journal={DNA repair},
  year={2014},
  volume={19},
  pages={71-83}
}
Maintaining high transcriptional fidelity is essential for life. Some DNA lesions lead to significant changes in transcriptional fidelity. In this review, we will summarize recent progress towards understanding the molecular basis of RNA polymerase II (Pol II) transcriptional fidelity and DNA lesion-induced transcriptional mutagenesis. In particular, we… CONTINUE READING