Molecular basis of salt sensitivity in human hypertension. Evaluation of renin-angiotensin-aldosterone system gene polymorphisms.

@article{Poch2001MolecularBO,
  title={Molecular basis of salt sensitivity in human hypertension. Evaluation of renin-angiotensin-aldosterone system gene polymorphisms.},
  author={Esteban Poch and Daniel Gonz{\'a}lez and Vicente Giner and Ernesto Bragulat and Antoni Coca and Alejandro de la Sierra},
  journal={Hypertension},
  year={2001},
  volume={38 5},
  pages={1204-9}
}
We analyzed the association between salt sensitivity in essential hypertension and 8 genetic polymorphisms in 6 genes of the renin-angiotensin aldosterone system. Seventy-one patients with essential hypertension were classified as salt sensitive or salt resistant by means of the 24-hour ambulatory blood pressure (BP) change to high salt intake. The polymorphisms evaluated correspond to the following genes: ACE (I/D), angiotensinogen (M235T), angiotensin II type 1 receptor (A1166C), 11beta… CONTINUE READING
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