Molecular basis of polymorphic drug metabolism

  • Ann K Daly
  • Published 1995 in Journal of Molecular Medicine


Genetic polymorphisms with functional effects occur in many of the genes encoding drug metabolizing enzymes and are an important cause of adverse drug reations. Recent advances in the understanding of the molecular genetics of drug-metabolizing enzymes, particularly the cytochromes P450, has enabled the molecular basis of several polymorphisms to be… (More)
DOI: 10.1007/BF00195139


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Cite this paper

@article{Daly1995MolecularBO, title={Molecular basis of polymorphic drug metabolism}, author={Ann K Daly}, journal={Journal of Molecular Medicine}, year={1995}, volume={73}, pages={539-553} }