Molecular basis of mechanical modulation of endothelial cell migration.

@article{Chien2005MolecularBO,
  title={Molecular basis of mechanical modulation of endothelial cell migration.},
  author={S H-L Chien and Song Li and Yang Ting Elizabeth Shiu and Yi-shuan Julie Li},
  journal={Frontiers in bioscience : a journal and virtual library},
  year={2005},
  volume={10},
  pages={
          1985-2000
        }
}
Vascular endothelial cells (ECs) play important roles in the regulation of vascular functions. Loss of endothelial integrity can lead to vascular diseases such as stenosis resulting from atherosclerosis. The migration of ECs into wounded area in the vessel wall is required for the restoration of its integrity and functions. EC migration results from a balance of externally applied forces (e.g. shear stress), intracellular forces (e.g., those generated by contractile and cytoskeletal proteins… CONTINUE READING

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