Molecular basis of human immunodeficiency virus type 1 drug resistance: overview and recent developments.

Abstract

The introduction of potent combination therapies in the mid-90s had a tremendous effect on AIDS mortality. However, drug resistance has been a major factor contributing to antiretroviral therapy failure. Currently, there are 26 drugs approved for treating human immunodeficiency virus (HIV) infections, although some of them are no longer prescribed. Most of… (More)
DOI: 10.1016/j.antiviral.2013.01.007

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